Update:
I removed the internal SATA disk, a 4TB WD red and resumed working.
The WD is new and inserted the other yesterday and used until this morning.
I have inserted a 2.5 disk and see it very well.
Through PC and host usb the WD red is read from the PC.
Tips

re-updating
Re installed 2.5 and the disk is seen. From testing the problem was the, fil manager ES that blocks everything.
I installed another file manager and the Q10 does not hang but the 4-TB disk is not seen.
However, it is seen from the file manager supplied with the firmware.
With 5.1 this did not happen and the q10 file manager does not allow you to copy the hidden files