I had had a chance to tinker a bit more. I had 2x 3tb desktop hard drives, and 2x 2tb portable hard drives all USB 3.0 plugged into the USB 3.0 port of the Q10, all through a powered 7 port USB 3.0 hub.
I tried playing those movies previously mentioned in my last email and each kept crashing and showing the "video problem" confirm error message after about 20 minutes or so multiple times.
On a hunch I disconnected all the drives and connected the Toshiba 2tb portable and played mad Max again all the way through without a hitch. I connected the 2tb WD portable hard drive today and played Warcraft all the way through as well without a hitch.
Does this issue sound familiar? Does the himedia not like multiple drives being fed through one port?
I hope this give you enough info.